1-Pyrrolidinecarboxylic acid, 2-(chlorocarbonyl)-, phenylmethyl ester, (2R)-
(R)-N-[(phenylmethoxy)carbonyl]-2-pyrrolidinecarbonyl chloride
CAS: 61350-62-7
Molecular Formula: C13H14ClNO3
1-Pyrrolidinecarboxylic acid, 2-(chlorocarbonyl)-, phenylmethyl ester, (2R)- - Names and Identifiers
1-Pyrrolidinecarboxylic acid, 2-(chlorocarbonyl)-, phenylmethyl ester, (2R)- - Physico-chemical Properties
| Molecular Formula | C13H14ClNO3 |
| Molar Mass | 267.70816 |
1-Pyrrolidinecarboxylic acid, 2-(chlorocarbonyl)-, phenylmethyl ester, (2R)- - Upstream Downstream Industry
| Downstream Products | (R)-5-BROMO-3-[(1-METHYL-2-PYRROLIDINYL)METHYL]-1H-INDOLE |
1-Pyrrolidinecarboxylic acid, 2-(chlorocarbonyl)-, phenylmethyl ester, (2R)- - Introduction
(R)-N-[(phenylmethoxy)carbonyl]-2-pyrrolidinecarbonyl chloride is a chemical substance whose molecular formula is C18H20ClNO3. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
(R)-N-[(phenylmethoxy)carbonyl]-2-pyrrolidinecarbonyl chloride is a solid with a white to yellowish color. It is insoluble in water at room temperature, but soluble in organic solvents such as ether, methanol and chloroform. Its melting point is about 65-70°C.
Use:
This compound is an important intermediate in organic synthesis. It is widely used in the field of drug synthesis, especially plays an important role in the synthesis of chiral compounds or drugs. It can be used to synthesize anticancer drugs, anti-inflammatory drugs, antibiotics and other bioactive molecules.
Method:
The preparation of (R)-N-[(phenylmethoxy)carbonyl]-2-pyrrolidinecarbonyl chloride generally involves two steps. First, benzylchloroformyl chloride (benzyl chloroformate) is reacted with 2-pyrrolidone (2-pyrrolidinone) by an appropriate reaction to give (R)-N-[(phenylmethoxy)carbonyl]-2-pyrrolidinone this intermediate. The resulting intermediate is then converted to (R)-N-[(phenylmethoxy)carbonyl]-2-pyrrolidinecarbonyl chloride using sublimation or crystallization methods.
Safety Information:
(R)-N-[(phenylmethoxy)carbonyl]-2-pyrrolidinecarbonyl chloride is a chemical that requires compliance with appropriate safety procedures. It may be irritating to the eyes, skin and respiratory system, so contact with skin, eyes and inhalation of its volatiles should be avoided at the time of contact. Wear appropriate personal protective equipment, such as goggles, gloves and protective masks. If contact or inhalation occurs, rinse immediately with plenty of water and seek medical help. During storage and handling, contact with oxidizing agents and strong acids should be avoided. Detailed safety information can be found in the relevant information.
Nature:
(R)-N-[(phenylmethoxy)carbonyl]-2-pyrrolidinecarbonyl chloride is a solid with a white to yellowish color. It is insoluble in water at room temperature, but soluble in organic solvents such as ether, methanol and chloroform. Its melting point is about 65-70°C.
Use:
This compound is an important intermediate in organic synthesis. It is widely used in the field of drug synthesis, especially plays an important role in the synthesis of chiral compounds or drugs. It can be used to synthesize anticancer drugs, anti-inflammatory drugs, antibiotics and other bioactive molecules.
Method:
The preparation of (R)-N-[(phenylmethoxy)carbonyl]-2-pyrrolidinecarbonyl chloride generally involves two steps. First, benzylchloroformyl chloride (benzyl chloroformate) is reacted with 2-pyrrolidone (2-pyrrolidinone) by an appropriate reaction to give (R)-N-[(phenylmethoxy)carbonyl]-2-pyrrolidinone this intermediate. The resulting intermediate is then converted to (R)-N-[(phenylmethoxy)carbonyl]-2-pyrrolidinecarbonyl chloride using sublimation or crystallization methods.
Safety Information:
(R)-N-[(phenylmethoxy)carbonyl]-2-pyrrolidinecarbonyl chloride is a chemical that requires compliance with appropriate safety procedures. It may be irritating to the eyes, skin and respiratory system, so contact with skin, eyes and inhalation of its volatiles should be avoided at the time of contact. Wear appropriate personal protective equipment, such as goggles, gloves and protective masks. If contact or inhalation occurs, rinse immediately with plenty of water and seek medical help. During storage and handling, contact with oxidizing agents and strong acids should be avoided. Detailed safety information can be found in the relevant information.
Last Update：2024-04-09 21:01:54
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Product Name: (R)-N-[(phenylmethoxy)carbonyl]-2-pyrrolidinecarbonyl chloride Visit Supplier Webpage Request for quotation
CAS: 61350-62-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 61350-62-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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Downstream Products for 1-Pyrrolidinecarboxylic acid, 2-(chlorocarbonyl)-, phenylmethyl ester, (2R)-